Targeting the AKT/cyclin D1 pathway to overcome intrinsic and acquired radioresistance of tumors for effective radiotherapy
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2016.1257832
Abstract: Abstract Purpose: Radiotherapy (RT) is a powerful tool in the treatment of cancer, having the advantage of preserving normal tissues. Clinical outcomes of RT are significantly improved by technological advances, enabling increased radiation doses directed… read more here.
Keywords: acquired radioresistance; tumor radioresistance; akt cyclin; radioresistance ... See more keywords
The Mechanism of Long Non-coding RNA in Cancer Radioresistance/Radiosensitivity: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.879704
Abstract: Background and purpose: Radioresistance remains a significant challenge in tumor therapy. This systematic review aims to demonstrate the role of long non-coding RNA (lncRNA) in cancer radioresistance/radiosensitivity. Material and methods: The electronic databases Pubmed, Embase,… read more here.
Keywords: non coding; systematic review; tumor radioresistance; tumor ... See more keywords
CircRNAs in Tumor Radioresistance
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DOI: 10.3390/biom12111586
Abstract: Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act… read more here.
Keywords: circrnas tumor; tumor; radioresistance; tumor radioresistance ... See more keywords
The Role of Hypoxia and the Immune System in Tumor Radioresistance
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11101555
Abstract: Radiotherapy is given to a majority of patients with cancer, and remains one of the most (cost)effective treatment options available [...]. read more here.
Keywords: tumor radioresistance; role hypoxia; immune system; hypoxia immune ... See more keywords