Time Trends in Use of Radical Prostatectomy by Tumor Risk and Life Expectancy in a National Veterans Affairs Cohort
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.12214
Abstract: Key Points Question How has the use of radical prostatectomy (RP) changed over time with respect to tumor risk and life expectancy (LE)? Findings In this cohort study of 5736 men treated with RP at… read more here.
Keywords: use radical; risk; risk tumors; tumor risk ... See more keywords
The contribution of WTAP gene variants to Wilms tumor susceptibility.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144839
Abstract: Wilms tumor is the most frequently occurring pediatric renal malignancy. Wilms tumor suppressor-1-associated protein (WTAP) is a vital component of N6-methyltransferase complex involved in tumorigenesis. However, the roles of WTAP gene single nucleotide polymorphisms (SNPs)… read more here.
Keywords: wtap gene; tumor risk; wilms tumor; tumor ... See more keywords
Abstract 5227: Cross-trait genome-wide association meta-analyses of clonal hematopoiesis and solid tumor risk
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5227
Abstract: Clonal hematopoiesis (CH) is an age-related phenomenon where hematopoietic stem cells and their progeny acquire specific somatic mutations in a small, well-defined set of leukemogenic genes conferring them with fitness advantage leading to clonal proliferation.… read more here.
Keywords: trait; tumor risk; risk; solid tumor ... See more keywords
Characterization and Childhood Tumor Risk Assessment of Genetic and Epigenetic Syndromes Associated With Lateralized Overgrowth
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2020.613260
Abstract: Lateralized overgrowth (LO), or segmental overgrowth, is defined as an increase in growth of tissue (bone, muscle, connective tissue, vasculature, etc.) in any region of the body. Some overgrowth syndromes, characterized by both generalized and… read more here.
Keywords: lateralized overgrowth; tumor risk; genetic epigenetic; overgrowth ... See more keywords