Multisite tumor sampling enhances the detection of intratumor heterogeneity at all different temporal stages of tumor evolution
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2223-y
Abstract: Intratumor heterogeneity (ITH) is an inherent process of tumor development that has received much attention in previous years, as it has become a major obstacle for the success of targeted therapies. ITH is also temporally… read more here.
Keywords: tumor sampling; intratumor heterogeneity; multisite tumor; tumor evolution ... See more keywords
ctDNA from ascites as an alternative to tumor sampling for HRD (homologous recombination deficiency) testing in ovarian cancer (OC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.6066
Abstract: 6066Background: Knowledge regarding HRD status is becoming crucial to guide maintenance strategies for patients with newly diagnosed OC. Unfortunately, for patients (pts) treated with neoadjuvant c... read more here.
Keywords: sampling hrd; ctdna ascites; hrd homologous; tumor sampling ... See more keywords