Circumventing intratumoral heterogeneity to identify potential therapeutic targets in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.03.005
Abstract: BACKGROUND & AIMS Identifying target genetic mutations in hepatocellular carcinoma (HCC) for therapy is made challenging by intratumoral heterogeneity. Circulating cell-free DNAs (cfDNA) may contain a more complete mutational spectrum compared to a single tumor… read more here.
Keywords: single tumor; hepatocellular carcinoma; heterogeneity; intratumoral heterogeneity ... See more keywords