Isolation and Culture of Glioblastoma Brain Tumor Stem Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8805-1_2
Abstract: Cancer stem cells (CSCs) have been identified in glioblastoma (GBM) and are proposed to be the main actors of post-treatment recurrence contributing to the very dismal prognosis of this devastating disease. Consequently, this important population… read more here.
Keywords: tumor stem; biology; brain tumor; stem ... See more keywords
Transcriptional control of brain tumor stem cells by a carbohydrate binding protein.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109647
Abstract: Brain tumor stem cells (BTSCs) and intratumoral heterogeneity represent major challenges in glioblastoma therapy. Here, we report that the LGALS1 gene, encoding the carbohydrate binding protein, galectin1, is a key regulator of BTSCs and glioblastoma… read more here.
Keywords: carbohydrate binding; tumor stem; binding protein; brain tumor ... See more keywords
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
Sign Up to like & getrecommendations! Published in 2017 at "BMC Neurology"
DOI: 10.1186/s12883-017-0843-0
Abstract: BackgroundJuglone is a natural pigment, which has cytotoxic effect against various human tumor cells. However, its cytotoxicity to glioma cells, especially to tumor stem-like cells (TSCs) has not been demonstrated.MethodsTSCs of glioma were enriched from… read more here.
Keywords: ros p38; like cells; juglone; tumor stem ... See more keywords
Riluzole: a potential therapeutic intervention in human brain tumor stem-like cells.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18043
Abstract: A small subpopulation of tumor stem-like cells has the capacity to initiate tumors and mediate radio- and chemoresistance in diverse cancers hence also in glioblastoma (GBM). It has been reported that this capacity of tumor… read more here.
Keywords: like cells; tumor stem; stem like; brain tumor ... See more keywords
In Vitro Validation of the Therapeutic Potential of Dendrimer-Based Nanoformulations against Tumor Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105691
Abstract: Tumor cells with stem cell properties are considered to play major roles in promoting the development and malignant behavior of aggressive cancers. Therapeutic strategies that efficiently eradicate such tumor stem cells are of highest clinical… read more here.
Keywords: cell; dendrimer based; tumor stem; stem ... See more keywords