Modeling and correct the GC bias of tumor and normal WGS data for SCNA based tumor subclonal population inferring
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DOI: 10.1186/s12859-018-2099-0
Abstract: BackgroundSomatic copy number alternations (SCNAs) can be utilized to infer tumor subclonal populations in whole genome seuqncing studies, where usually their read count ratios between tumor-normal paired samples serve as the inferring proxy. Existing SCNA… read more here.
Keywords: tumor subclonal; tumor normal; scna based; subclonal population ... See more keywords