Pancreatic Tumor-targeting Stemsome Therapeutics.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202300934
Abstract: Owing to the intrinsic ability of stem cells to target the tumor environment, stem cell membrane-functionalized nanocarriers can target and load active anticancer drugs. In this study, a strategy that focuses on stem cells that… read more here.
Keywords: tumor targeting; targeting stemsome; pancreatic tumor; tumor ... See more keywords
Tumor Microenvironment‐Triggered Aggregated Magnetic Nanoparticles for Reinforced Image‐Guided Immunogenic Chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201802134
Abstract: Abstract Anticancer therapies, which can induce cell death and elevate antitumor immune response in the meantime, are considered as effective treatments for many types of cancers. Immunogenic cell death (ICD) induced by chemodrugs is a… read more here.
Keywords: etp ptfenp; magnetic nanoparticles; icd; tumor targeting ... See more keywords
Role of Surface RGD Patterns on Protein Nanocages in Tumor Targeting Revealed Using Precise Discrete Models.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201904838
Abstract: The effectiveness of active targeting in cancer nanomedicine is becoming increasingly more debatable. Here, the role of the ligand functionalization patterns (number and distribution) on nanoparticle surfaces in tumor targeting is investigated using a 9… read more here.
Keywords: ligand dps; surface; tumor targeting; role ... See more keywords
Nanobugs as Drugs: Bacterial Derived Nanomagnets Enhance Tumor Targeting and Oncolytic Activity of HSV-1 Virus.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202104763
Abstract: The survival strategies of infectious organisms have inspired many therapeutics over the years. Indeed the advent of oncolytic viruses (OVs) exploits the uncontrolled replication of cancer cells for production of their progeny resulting in a… read more here.
Keywords: bacterial derived; tumor targeting; nanobugs drugs; drugs bacterial ... See more keywords
An off-on fluorescence probe targeting mitochondria based on oxidation-reduction response for tumor cell and tissue imaging
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-017-4030-4
Abstract: AbstractIn this study, a tumor-targeting poly(d, l-lactic-co-glycolic acid) (PLGA) loaded “off-on” fluorescent probe nanoparticle (PFN) delivery system was developed to evaluate the region of tumor by off-on fluorescence. The biodegradability of the nanosize PFN delivery… read more here.
Keywords: probe; fluorescence probe; tumor targeting; cancer ... See more keywords
A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole and nanosilver
Sign Up to like & getrecommendations! Published in 2018 at "Nano Research"
DOI: 10.1007/s12274-018-2032-x
Abstract: Although nanotechnology has been rapidly developed and applied in tumor targeting, the outcome of chemotherapy remains greatly restricted by the toxicity of cytotoxic drugs in normal tissues and cells. Therefore, the development of alternative delivery… read more here.
Keywords: energy restriction; albendazole nanosilver; energy; novel tumor ... See more keywords
Amino acid transporters: Emerging roles in drug delivery for tumor-targeting therapy
Sign Up to like & getrecommendations! Published in 2020 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2019.12.002
Abstract: Amino acid transporters, which play a vital role in transporting amino acids for the biosynthesis of mammalian cells, are highly expressed in types of tumors. Increasing studies have shown the feasibility of amino acid transporters… read more here.
Keywords: targeting therapy; acid transporters; tumor targeting; amino acid ... See more keywords
Tumor targeting peptides: novel therapeutic strategies in glioblastoma.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2019.01.006
Abstract: Peptides are a promising new therapeutic approach for glioblastoma with potential for more effective targeting and fewer devastating side effects compared to conventional cancer therapies. With the specificity to target receptors which are uniquely or… read more here.
Keywords: treatment; peptides novel; tumor targeting; targeting peptides ... See more keywords
3‐Carboxyphenylboronic acid‐modified carboxymethyl chitosan nanoparticles for improved tumor targeting and inhibitory
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2016.12.034
Abstract: Graphical abstract No caption available. Abstract Carboxymethyl chitosan‐based nanoparticles (CM NPs) were prepared, and were further modified with a tumor‐homing ligand (3‐carboxyphenylboronic acid, 3‐CPBA) to give tumor‐targeting nanoparticles (CB NPs). Particle sizes were measured by… read more here.
Keywords: carboxymethyl chitosan; dox nps; tumor targeting; dox ... See more keywords
Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.08.014
Abstract: ABSTRACT Ferritin nanocages are of particular interest as a novel platform for drug and vaccine delivery, diagnosis, biomineralization scaffold and more, due to their perfect and complex symmetry, ideal physical properties, high biocompatibility, low toxicity… read more here.
Keywords: ferritin; tumor targeting; half life; ferritin nanocages ... See more keywords
Mass Spectrometry-Based Method for the Determination of the Biodistribution of Tumor-Targeting Small Molecule-Metal Conjugates.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01104
Abstract: Nuclear medicine plays a key role in modern diagnosis and cancer therapy. The development of tumor-targeting radionuclide conjugates (also named small molecule-radio conjugates (SMRCs)) represents a significant improvement over the clinical use of metabolic radiotracers… read more here.
Keywords: small molecule; biodistribution; metal conjugates; tumor targeting ... See more keywords