Microenvironment‐Responsive Targeted Nanomedicine for a Collaborative Integration of Tumor Theranostics and Bone Defect Repair
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400715
Abstract: Despite advancements in breast cancer treatment, bone metastases remain a significant concern for advanced breast cancer patients. Current theranostics strategies face challenges in integrating tumor theranostics and bone formation. Herein, this work develops an activatable… read more here.
Keywords: theranostics bone; targeted nanomedicine; tumor theranostics; tumor ... See more keywords
Smart Nanogatekeepers for Tumor Theranostics.
Sign Up to like & getrecommendations! Published in 2021 at "Small"
DOI: 10.1002/smll.202103712
Abstract: Nanoparticulate drug delivery systems (nano-DDSs) are required to reliably arrive and persistently reside at the tumor site with minimal off-target side effects for clinical theranostics. However, due to the complicated environment and high interstitial pressure… read more here.
Keywords: structure; nanogatekeepers tumor; smart nanogatekeepers; tumor theranostics ... See more keywords
Conjugated Polymer Nanoparticles for Tumor Theranostics.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01446
Abstract: Water-dispersible conjugated polymer nanoparticles (CPNs) have demonstrated great capabilities in biological applications, such as in vitro cell/subcellular imaging and biosensing, or in vivo tissue imaging and disease treatment. In this review, we summarized the recent… read more here.
Keywords: nanoparticles tumor; conjugated polymer; polymer nanoparticles; treatment ... See more keywords
Cathepsin B-Activated Prodrug for Precision Tumor Theranostics.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.5c02241
Abstract: In response to the systemic toxicity associated with chemotherapeutic agents and the diverse characteristics of the tumor microenvironment, we present an innovative theranostic prodrug system, designated NM-001. NM-001 specifically targets the overexpressed integrin ανβ3 on… read more here.
Keywords: prodrug precision; tumor; tumor theranostics; cathepsin activated ... See more keywords
Aptamer-Exosomes for Tumor Theranostics.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.0c02237
Abstract: As carriers of biomolecules (proteins, nucleic acids, and lipids) from parent cells, exosomes play a significant role in physiology and pathology. In any diseased state, the morphology of the released exosomes remained similar. The contents… read more here.
Keywords: pathology; physiology; tumor theranostics; aptamer exosomes ... See more keywords
A glutathione-depleting chemodynamic therapy agent with photothermal and photoacoustic properties for tumor theranostics.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/c9nr09858e
Abstract: Nowadays, Fenton reaction-based chemodynamic therapy (CDT) strategies have drawn extensive attention as tumor-specific nanomedicine-based therapy. Nevertheless, current existing CDTs normally suffer from therapeutic bottlenecks such as the scavenging of hydroxyl radical (˙OH) by intracellular antioxidants… read more here.
Keywords: therapy; chemodynamic therapy; cdt agents; tumor theranostics ... See more keywords
Acid-Responsive Decomposable Nanomedicine Based on Zeolitic Imidazolate Frameworks for Near-Infrared Fluorescence Imaging/Chemotherapy Combined Tumor Theranostics
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics16060823
Abstract: Zeolitic imidazolate framework-8 (ZIF-8) nanoparticles (NPs) are gaining traction in tumor theranostics for their effectiveness in encapsulating both imaging agents and therapeutic drugs. While typically, similar hydrophilic molecules are encapsulated in either pure aqueous or… read more here.
Keywords: infrared fluorescence; chemotherapy; tumor theranostics; tumor ... See more keywords
Tumor-penetrating Peptide Conjugated and Doxorubicin Loaded T1-T2 Dual Mode MRI Contrast Agents Nanoparticles for Tumor Theranostics
Sign Up to like & getrecommendations! Published in 2018 at "Theranostics"
DOI: 10.7150/thno.21074
Abstract: The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. Methods: In this study, a tumor-penetrating peptide RGERPPR (RGE) modified, Gd-DTPA conjugated, and doxorubicin (DOX) loaded… read more here.
Keywords: rge; penetrating peptide; tumor penetrating; dox ... See more keywords