A Size-Changeable Collagenase-Modified Nanoscavenger for Increasing Penetration and Retention of Nanomedicine in Deep Tumor Tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.201906745
Abstract: The complex tumor microenvironment constitutes a variety of barriers to prevent nanoparticles (NPs) delivery and results in extremely low accumulation of nanomedicines in solid tumors. Here, a newly developed size-changeable collagenase-modified polymer micelle is employed… read more here.
Keywords: tumor tissue; penetration; collagenase; retention ... See more keywords
Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1935
Abstract: Liquid biopsy has provided an efficient way for detection of gene alterations in advanced non‐small‐cell lung cancer (NSCLC). However, the correlation between systematic determination of somatic genomic alterations in liquid biopsy and tumor biopsy still… read more here.
Keywords: tumor tissue; plasma; sputum; liquid biopsy ... See more keywords
A biomimetic tumor tissue phantom for validating diffusion‐weighted MRI measurements
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DOI: 10.1002/mrm.27016
Abstract: To develop a biomimetic tumor tissue phantom which more closely reflects water diffusion in biological tissue than previously used phantoms, and to evaluate the stability of the phantom and its potential as a tool for… read more here.
Keywords: tumor tissue; diffusion; tissue phantom; validating diffusion ... See more keywords
Heterogeneous blood flow in microvessels with applications to nanodrug transport and mass transfer into tumor tissue
Sign Up to like & getrecommendations! Published in 2019 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-018-1071-2
Abstract: Nanodrug transport in tumor microvasculature and deposition/extravasation into tumor tissue are an important link in the nanodrug delivery process. Considering heterogeneous blood flow, such a dual process is numerically studied. The hematocrit distribution is solved… read more here.
Keywords: blood flow; tumor tissue; transport; blood ... See more keywords
Study of possibility of cell recognition in brain tumors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers of Optoelectronics"
DOI: 10.1007/s12200-020-1095-y
Abstract: The brain has an exceptionally high requirement for energy metabolism, with glucose serving as the exclusive energy source. Cancers, including glioblastoma, have a high glucose uptake and rely on aerobic glycolysis for energy metabolism. The… read more here.
Keywords: tumor tissue; immune cells; brain; study possibility ... See more keywords
Expression of microRNA-21 in saliva and tumor tissue of patients with oral squamous cell carcinoma: a predictor of cervical lymph node metastasis.
Sign Up to like & getrecommendations! Published in 2021 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2021.07.012
Abstract: OBJECTIVE Evaluation of diagnostic accuracy of microRNA-21 (miR-21) in saliva and tumor tissue for presurgical assessment of lymph node metastasis in patients with oral squamous cell carcinoma (OSCC). STUDY DESIGN Unstimulated whole saliva and tumor… read more here.
Keywords: cervical lymph; lymph node; node metastasis; tumor tissue ... See more keywords
Presence of identical B-cell clone in both cerebrospinal fluid and tumor tissue in a patient with opsoclonus–myoclonus syndrome associated with neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2022.2109784
Abstract: Abstract Opsoclonus-myoclonus syndrome associated with neuroblastoma (OMS-NB) is a refractory paraneoplastic syndrome which often remain neurological sequelae, and detailed pathogenesis has remained elusive. We encountered a pediatric patient with OMS-NB treated by immunosuppressed therapy who… read more here.
Keywords: cell clone; cell; identical cell; tumor tissue ... See more keywords
NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2020.1845424
Abstract: ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is one of the most common tumor subtypes and remains associated with very poor survival. T cell infiltration into tumor tissue is associated with improved clinical outcome but little is… read more here.
Keywords: phenotype; tumor tissue; tumor; cells pancreatic ... See more keywords
Is the Mirror Image Method Really Useful in Tumor Tissue Bank Quality Control?
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DOI: 10.1089/bio.2018.0123
Abstract: Oncology research projects are highly dependent on the quality of tumor samples stored in the biobank. Microscopic control is important to ensure the quality of the frozen sample (Does the sample correspond to tumor tissue?… read more here.
Keywords: quality; tumor tissue; control; mirror ... See more keywords
Both plasma and tumor tissue miR-146a high expression correlates with prolonged overall survival of surgical patients with intrahepatic cholangiocarcinoma
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DOI: 10.1097/md.0000000000008267
Abstract: Abstract The purpose of this study was to investigate the association of tumor tissue and plasma miR-146a/b expressions with the clinicopathological properties and overall survival (OS) in surgical patients with intrahepatic cholangiocarcinomas (ICC). Eighty-seven patients… read more here.
Keywords: tumor tissue; plasma; mir 146a; tissue ... See more keywords
Pleural effusion as a substitute for tumor tissue in detecting EGFR/ALK mutations in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015450
Abstract: Background: Pleural effusion (PE) has been reported useful in many studies for testing epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) with variable results. This systematic review and meta-analysis was performed… read more here.
Keywords: egfr mutations; mutations non; tumor tissue; tumor ... See more keywords