Rapid visualizing and pathological grading of bladder tumor tissues by simple nanodiagnostics.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120434
Abstract: Developing a tissue diagnosis technology to avoid the complicated processes and the usage of expensive reagents while achieving rapid pathological grading diagnosis to provide a better strategy for clinical treatment is an important strategy of… read more here.
Keywords: rgd senps; tumor tissues; tissue; tumor ... See more keywords
Rational Design for Nitroreductase (NTR)-Responsive Proteolysis Targeting Chimeras (PROTACs) Selectively Targeting Tumor Tissues.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c02221
Abstract: The catalytic properties of proteolysis targeting chimeras (PROTACs) may lead to uncontrolled off-tissue target degradation that causes potential toxicity, limiting their clinical applications. The precise control of this technology in a tissue-selective manner can minimize… read more here.
Keywords: ntr responsive; chimeras protacs; proteolysis targeting; tumor tissues ... See more keywords
LC-HRMS based approach to identify novel sphingolipid biomarkers in breast cancer patients
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61283-w
Abstract: Perturbations in lipid metabolic pathways to meet the bioenergetic and biosynthetic requirements is a principal characteristic of cancer cells. Sphingolipids (SPLs) are the largest class of bioactive lipids associated to various aspects of tumorigenesis and… read more here.
Keywords: tumor tissues; breast cancer; approach identify; tcga cohort ... See more keywords
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2114282119
Abstract: Significance Immunosuppressive Foxp3-expressing regulatory T cells (Tregs) in tumor tissues are assumed to be clonally expanding via recognizing tumor-associated antigens. By single-cell RNA sequencing, we have searched for the molecules that are specifically expressed by… read more here.
Keywords: tumor tregs; cell; tumor; tumor tissues ... See more keywords
Banking of Tumor Tissues: Effect of Preanalytical Variables in the Phase of Pre- and Postacquisition on RNA Integrity.
Sign Up to like & getrecommendations! Published in 2022 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2021.0124
Abstract: Background: RNA integrity of tumor tissues from 12 common organs was measured, and tumor tissues from liver were found to have the best RNA integrity in our previous study. The effects of preanalytical variables in… read more here.
Keywords: rna integrity; preanalytical variables; tumor; tumor tissues ... See more keywords
Expression of PD-L1 in plasma exosomes of NSCLC patients and its associations with PD-L1 expression of corresponding tumour tissues
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz239.049
Abstract: Abstract Background The aim of this study was to research whether there was expression of PD-L1 in plasma exosome of NSCLC patients and whether its expression can partly represent PD-L1 expression of corresponding lung tumor… read more here.
Keywords: nsclc patients; tumor tissues; exosomal expression; expression ... See more keywords
Decrease of 5-hydroxymethylcytosine in hepatitis B virus-related hepatocellular carcinoma: A cross-sectional study
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033943
Abstract: Many epigenetic studies had found the decrease of 5-hydroxymethylcytosine (5-hmC) in various tumor tissues. However, limited information is available for hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC). The present study aimd to investigate whether the… read more here.
Keywords: decrease; virus related; tumor tissues; hepatitis virus ... See more keywords
EP791 Dissociation between systemic and local hormonal profiles in young patients with ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.842
Abstract: Introduction/Background Blood levels of hormones do not reflect the true picture of hormonal homeostasis due to the local synthesis of sex hormones by tumor tissues. Our purpose was to analyze levels and ratios of sex… read more here.
Keywords: 4n1 2m0; tumor tissues; blood; ovarian cancer ... See more keywords
Similarity and difference in tumor-infiltrating lymphocytes in original tumor tissues and those of in vitro expanded populations in head and neck cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.23454
Abstract: Though adoptive tumor-infiltrating lymphocyte (TIL) therapy has been explored in clinical trials for many years, there is little information for the clonotype composition between TILs in original tumor tissues and TILs that were in vitro… read more here.
Keywords: vitro expanded; tumor tissues; original tumor; tumor infiltrating ... See more keywords
Expression and clinical significance of miR-17-5p in tumor tissues of patients with colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-1185
Abstract: Background At present, there is a lack of novel biomarkers for the early diagnosis and targeted therapy of colorectal cancer (CRC). The current study investigated the expression of miR-17-5p in colorectal tumors and adjacent tissues,… read more here.
Keywords: cell; tumor tissues; expression; mir ... See more keywords
Role of miR-193a-5p in the proliferation and apoptosis of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201811_16257
Abstract: OBJECTIVE This study aims at exploring the regulatory effects of miR-193a-5p on hepatocellular carcinoma (HCC). It might provide new insight into the improvement of clinical treatment of HCC. PATIENTS AND METHODS A total of 50… read more here.
Keywords: hcc; apoptosis; tumor tissues; proliferation ... See more keywords