High‐Z‐Sensitized Radiotherapy Synergizes with the Intervention of the Pentose Phosphate Pathway for In Situ Tumor Vaccination
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DOI: 10.1002/adma.202109726
Abstract: In situ tumor vaccination is preliminarily pursued to strengthen antitumor immune response. Immunogenic tumor cell death spontaneously releases abundant antigens and adjuvants for activation of dendritic cells, providing a paragon opportunity for establishing efficient in… read more here.
Keywords: phosphate pathway; vaccination; pentose phosphate; tumor vaccination ... See more keywords
Deep Tumor Penetrating Gold Nano-Adjuvant for NIR-II-Triggered In Situ Tumor Vaccination.
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DOI: 10.1002/smll.202200993
Abstract: Local tumor photothermal treatment with the near-infrared light at the second window (NIR-II) is a promising strategy in triggering the in situ tumor vaccination (ISTV) for cancer therapy. However, limited penetration of photothermal agents within… read more here.
Keywords: deep tumor; nano adjuvant; tumor vaccination; situ tumor ... See more keywords
Engineered bacteria for augmented in situ tumor vaccination.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01593e
Abstract: In situ tumor vaccination has aroused tremendous interest with its capability for eliciting strong and systemic antitumor immune responses. Unlike traditional cancer vaccines, in situ tumor vaccination avoids the laborious process of tumor antigen identification… read more here.
Keywords: bacteria augmented; vaccination; tumor vaccination; engineered bacteria ... See more keywords
In-situ tumor vaccination by percutaneous ablative therapy and its synergy with immunotherapeutics: An update on combination therapy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1118845
Abstract: Percutaneous tumor ablation is now a widely accepted minimally invasive local treatment option offered by interventional radiology and applied to various organs and tumor histology types. It utilizes extreme temperatures to achieve irreversible cellular injury,… read more here.
Keywords: ablation; tumor vaccination; therapy; situ tumor ... See more keywords
Application of Organoids in Carcinogenesis Modeling and Tumor Vaccination
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DOI: 10.3389/fonc.2022.855996
Abstract: Organoids well recapitulate organ-specific functions from their tissue of origin and remain fundamental aspects of organogenesis. Organoids are widely applied in biomedical research, drug discovery, and regenerative medicine. There are various cultivated organoid systems induced… read more here.
Keywords: application organoids; medicine; tumor vaccination; tumor ... See more keywords
Dendritic Cell Tumor Vaccination via Fc Gamma Receptor Targeting: Lessons Learned from Pre-Clinical and Translational Studies
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DOI: 10.3390/vaccines9040409
Abstract: Despite significant recent improvements in the field of immunotherapy, cancer remains a heavy burden on patients and healthcare systems. In recent years, immunotherapies have led to remarkable strides in treating certain cancers. However, despite the… read more here.
Keywords: translational studies; cell; gamma; tumor vaccination ... See more keywords