Trimodal Therapy: A Tumor Vascular‐Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia (Adv. Sci. 8/2018)
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DOI: 10.1002/advs.201870048
Abstract: A tumor vascular‐targeted interlocking trimodal nanosystem that induces and exploits hypoxia is described by Hong‐Zhuan Chen, Chao Fang, and co‐workers in article number https://doi.org/10.1002/advs.201800034. In the image, the two streams of water from bamboo pipes… read more here.
Keywords: vascular; interlocking trimodal; tumor vascular; vascular targeted ... See more keywords
Imaging acute effects of bevacizumab on tumor vascular kinetics in a preclinical orthotopic model of U251 glioma
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DOI: 10.1002/nbm.4516
Abstract: The effect of a human vascular endothelial growth factor antibody on the vasculature of human tumor grown in rat brain was studied. Using dynamic contrast‐enhanced magnetic resonance imaging, the effects of intravenous bevacizumab (Avastin; 10… read more here.
Keywords: tumor vascular; orthotopic; time; vascular kinetics ... See more keywords
Erythrocyte Membrane-Coated Invisible Acoustic-Sensitive Nanoparticle for Inducing Tumor Thrombotic Infarction by Precisely Damaging Tumor Vascular Endothelium.
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DOI: 10.1002/smll.202201933
Abstract: Selective induction of tumor thrombus infarction is a promising antitumor strategy. Non-persistent embolism due to non-compacted thrombus and activated fibrinolytic system within the tumor large blood vessels and tumor margin recurrence are the main therapeutic… read more here.
Keywords: tumor vascular; damaging tumor; infarction; vascular endothelium ... See more keywords
Targetoid appearance on T2-weighted imaging and signs of tumor vascular involvement: diagnostic value for differentiating HCC from other primary liver carcinomas
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DOI: 10.1007/s00330-021-07743-x
Abstract: To evaluate targetoid appearance on T2-weighted imaging and signs of tumor vascular involvement as potential new LI-RADS features for differentiating hepatocellular carcinoma (HCC) from other non-HCC primary liver carcinomas (PLCs). This IRB-approved, retrospective study was… read more here.
Keywords: appearance weighted; vascular involvement; tumor vascular; targetoid appearance ... See more keywords
A microfluidic device for study of the effect of tumor vascular structures on the flow field and HepG2 cellular flow behaviors.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.035
Abstract: To build a microfluidic device with various morphological features of the tumor vasculature for study of the effects of tumor vascular structures on the flow field and tumor cellular flow behaviors. The designed microfluidic device… read more here.
Keywords: flow field; microfluidic device; vascular structures; tumor vascular ... See more keywords
Mechanosensitive TRPV4 channels stabilize VE-cadherin junctions to regulate tumor vascular integrity and metastasis.
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DOI: 10.1016/j.canlet.2018.07.042
Abstract: The transient receptor potential vanilloid 4 (TRPV4) channel is a mechanosensor in endothelial cells (EC) that regulates cyclic strain-induced reorientation and flow-mediated nitric oxide production. We have recently demonstrated that TRPV4 expression is reduced in… read more here.
Keywords: tumor vascular; vascular integrity; metastasis; cell ... See more keywords
Exercise during preoperative therapy increases tumor vascularity in pancreatic tumor patients
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DOI: 10.1038/s41598-019-49582-3
Abstract: The efficacy of chemotherapy is reduced by dysfunctional tumor vasculature, which may limit chemotherapy delivery to tumors. Preclinical studies have shown that moderate aerobic exercise improves tumor vascular function and increases chemotherapy efficacy in mouse… read more here.
Keywords: chemotherapy; tumor vascular; tumor vasculature; therapy ... See more keywords
Abstract 5012: Exercise as a novel method of tumor vascular remodeling
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DOI: 10.1158/1538-7445.am2020-5012
Abstract: Chemotherapy efficacy is reliant upon access to tumor cells. One method of increasing chemotherapy response is to enhance delivery of chemotherapy to the tumor by vascular normalization. Tumor vasculature is largely dysfunctional, leading to poor… read more here.
Keywords: tumor vascular; shear stress; permeability; vascular remodeling ... See more keywords
Tumor vascular normalization monitor by non-contrast intravoxel incoherent motion diffusion-weighted MRI.
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DOI: 10.1200/jco.2018.36.15_suppl.e15707
Abstract: e15707Background: Tumor vascular normalization has been proposed as a new concept for anti-tumor angiogenesis, and the normalization time window had been considered as an opportunity to improve dru... read more here.
Keywords: monitor non; normalization monitor; tumor vascular; vascular normalization ... See more keywords
Mesenchymal-epithelial Transition and Tumor Vascular Remodeling in Eribulin Chemotherapy for Breast Cancer.
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DOI: 10.21873/anticanres.12236
Abstract: BACKGROUND/AIM Eribulin mesylate (eribulin) is currently used for the treatment of locally advanced or metastatic breast cancer (MBC). It is a cytotoxic agent with unique mechanisms that suppress the epithelial-mesenchymal transition (EMT) of cancer cells… read more here.
Keywords: tumor vascular; treatment; breast cancer; expression ... See more keywords
Tumor vascular heterogeneity and the impact of subtumoral nanoemulsion biodistribution.
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DOI: 10.2217/nnm-2022-0176
Abstract: Aim: Investigate the heterogeneous tumor tissue organization and examine how this condition can interfere with the passive delivery of a lipid nanoemulsion in two breast cancer preclinical models (4T1 and Ehrlich). Materials & methods: The… read more here.
Keywords: tumor vascular; nanoemulsion biodistribution; nanoemulsion; vascular heterogeneity ... See more keywords