Abstract 4044: LY3039579, a novel Notch inhibit, potentiates the anti-tumoral effects of sorafenib in hepatocellular carcinoma (HCC)
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DOI: 10.1158/1538-7445.am2017-4044
Abstract: Introduction: Notch pathway has been involved in cell fate determination, cell differentiation, proliferation and death. Notch promotes cell survival, angiogenesis and treatment resistance in numerous cancers, making it a promising target for cancer therapy. The… read more here.
Keywords: novel notch; notch; anti tumoral; ly3039478 ... See more keywords
In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma
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DOI: 10.3389/fphar.2017.00373
Abstract: Malignant mesothelioma (MM) is a tumor arising from mesothelium. MM patients’ survival is poor. The polyphenol 4′,5,7,-trihydroxyflavone Apigenin (API) is a “multifunctional drug”. Several studies have demonstrated API anti-tumoral effects. However, little is known on… read more here.
Keywords: vitro vivo; vivo anti; anti tumoral; tumoral effects ... See more keywords