Ecto-calreticulin expression in multiple myeloma correlates with a failed anti-tumoral immune response and bad prognosis
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2141973
Abstract: ABSTRACT Immunogenic cell death (ICD) has been proposed to be a crucial process for antitumor immunosurveillance. ICD is characterized by the exposure and emission of Damage Associated Molecular Patterns (DAMP), including calreticulin (CRT). A positive… read more here.
Keywords: anti tumoral; prognosis; expression; crt ... See more keywords
Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward
Sign Up to like & getrecommendations! Published in 2021 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2021-003013
Abstract: Tumors accumulate metabolites that deactivate infiltrating immune cells and polarize them toward anti-inflammatory phenotypes. We provide a comprehensive review of the complex networks orchestrated by several of the most potent immunosuppressive metabolites, highlighting the impact… read more here.
Keywords: metabolites tumoral; tumoral immune; immune evasion; evasion redundancies ... See more keywords