Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS computational biology"
DOI: 10.1371/journal.pcbi.1009606
Abstract: The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified. However,… read more here.
Keywords: tumorigenesis degeneration; tissue homeostasis; tissue; coupled bidirectional ... See more keywords