DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals
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DOI: 10.1038/s41388-019-1085-y
Abstract: The DEPTOR-mTORC1/2 axis has been shown to play an important, but a context dependent role in the regulation of proliferation and the survival of various cancer cells in cell culture settings. The in vivo role… read more here.
Keywords: prostate tumorigenesis; tumor suppressor; mtorc1; tumorigenesis via ... See more keywords