Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
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DOI: 10.1038/s41598-017-09662-8
Abstract: Cultured cancer cells serve as important models for preclinical testing of anti-cancer compounds. However, the optimal conditions for retaining original tumor features during in vitro culturing of cancer cells have not been investigated in detail.… read more here.
Keywords: tumorigenic metastatic; cells cultured; serum; differentiation ... See more keywords