Hes1 in malignant tumors: from molecular mechanism to therapeutic potential
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DOI: 10.3389/fimmu.2025.1585624
Abstract: The occurrence and development of malignant tumors involve abnormalities in complex molecular regulatory networks, among which the abnormal activation of the transcriptional regulator hairy and enhancer of split 1 (Hes1) has attracted significant attention in… read more here.
Keywords: tumors molecular; molecular mechanism; hes1; potential hes1 ... See more keywords
Parathyroid Tumors: Molecular Signatures
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DOI: 10.3390/ijms222011206
Abstract: Parathyroid tumors are rare endocrine neoplasms affecting 0.1–0.3% of the general population, including benign parathyroid adenomas (PAs; about 98% of cases), intermediate atypical parathyroid adenomas (aPAs; 1.2–1.3% of cases) and malignant metastatic parathyroid carcinomas (PCs;… read more here.
Keywords: molecular signatures; parathyroid tumors; tumors molecular;
Decoding Pancreatic Neuroendocrine Tumors: Molecular Profiles, Biomarkers, and Pathways to Personalized Therapy
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DOI: 10.3390/ijms26167814
Abstract: Pancreatic neuroendocrine tumors (pNETs) are rare malignancies, accounting for 1–2% of pancreatic cancers, with an incidence of ≤1 case per 100,000 individuals annually. Originating from pancreatic endocrine cells, pNETs display significant clinical and biological heterogeneity.… read more here.
Keywords: therapy; tumors molecular; pancreatic neuroendocrine; neuroendocrine tumors ... See more keywords