Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13287
Abstract: In glioblastoma (GBM), tumour‐associated microglia/macrophages (TAMs) represent the major cell type of the stromal compartment and contribute to tumour immune escape mechanisms. Thus, targeting TAMs is emerging as a promising strategy for immunotherapy. However, TAM… read more here.
Keywords: associated microglia; microglia macrophage; progression; tumour ... See more keywords
Relationship between R1 resection, tumour rupture and recurrence in resected gastrointestinal stromal tumour
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Surgery"
DOI: 10.1002/bjs.11027
Abstract: According to guidelines, adjuvant treatment or re‐excision should be considered after R1 resection of gastrointestinal stromal tumours (GISTs). However, the prognostic significance of R1 resection is uncertain and tumour rupture confounds its assessment. Here, the… read more here.
Keywords: relationship resection; tumour rupture; tumour; gastrointestinal stromal ... See more keywords
Comment on: Role of tumour location and surgical extent on prognosis in T2 gallbladder cancer
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11881
Abstract: Editor Kwon et al reported the “Role of tumour location and surgical extent on prognosis in T2 gallbladder cancer: an international multicentre study”1. Authors concluded lack of impact of tumour location (T2) on disease free… read more here.
Keywords: role tumour; location surgical; tumour location; surgical extent ... See more keywords
Human pancreatic tumour organoid‐derived factors enhance myogenic differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12917
Abstract: Most patients with pancreatic cancer develop cachexia, which is characterized by progressive muscle loss. The mechanisms underlying muscle loss in cancer cachexia remain elusive. Pancreatic tumour organoids are 3D cell culture models that retain key… read more here.
Keywords: tumour organoid; pancreatic tumour; muscle; tumour ... See more keywords
Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant KRAS DNA early in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12142
Abstract: Abstract Up to now, the field of liquid biopsies has focused on circulating tumour DNA and cells, though extracellular vesicles (EVs) have been of increasing interest in recent years. Thus, reported sources of tumour‐derived nucleic… read more here.
Keywords: extracellular vesicles; mutant kras; kras dna; tumour derived ... See more keywords
Endothelial extracellular vesicles promote tumour growth by tumour‐associated macrophage reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12228
Abstract: Abstract Tumour‐derived extracellular vesicles (EVs) participate in tumour progression by deregulating various physiological processes including angiogenesis and inflammation. Here we report that EVs released by endothelial cells in a mammary tumour environment participate in the… read more here.
Keywords: tumour growth; extracellular vesicles; tumour; vesicles promote ... See more keywords
Feasibility of multi-parametric PET and MRI for prediction of tumour recurrence in patients with glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-018-4180-3
Abstract: BackgroundRecurrence in glioblastoma patients often occur close to the original tumour and indicates that the current treatment is inadequate for local tumour control. In this study, we explored the feasibility of using multi-modality imaging at… read more here.
Keywords: recurrence; radiotherapy; tumour recurrence; pet mri ... See more keywords
[68Ga]Ga-DOTA-FAPI-04 PET/CT imaging of benign pulmonary solitary fibrous tumour
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05199-1
Abstract: A 27-year-old man with persistent cough and headache for 2months was referred to our hospital for further evaluation after a chest radiography revealed a large mass in the right lung. History revealed that he had… read more here.
Keywords: fapi pet; solitary fibrous; fibrous tumour; tumour ... See more keywords
How safe and effective is denosumab for bone giant cell tumour?
Sign Up to like & getrecommendations! Published in 2017 at "International Orthopaedics"
DOI: 10.1007/s00264-017-3536-9
Abstract: Recent clinical studies have suggested that denosumab is associated with beneficial tumour response, surgical down-staging, and reduced surgical morbidity in patients with giant cell tumour of bone. However, these studies reported results of patients still… read more here.
Keywords: cell tumour; giant cell; denosumab; bone ... See more keywords
The Simultaneous Presence of Isolated Tumour Cells and Bone Marrow Micrometastases in Stage I and II Colon Cancer—Challenging the Theory of a Chronological Pathway of Tumour Cell Dissemination
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Surgery"
DOI: 10.1007/s00268-021-06399-4
Abstract: According to the common tenet, tumour progression is a chronological process starting with lymphatic invasion. In this respect, the meaning of bone marrow micrometastases (BMM) in patients with lymph node negative colon cancer (CC) is… read more here.
Keywords: marrow micrometastases; tumour; isolated tumour; colon cancer ... See more keywords
Commentary on “CTLA-4 Blockade Suppresses Progression of Residual Tumours after Insufficient RFA”
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular and Interventional Radiology"
DOI: 10.1007/s00270-020-02564-9
Abstract: Image-guided tumour ablation has developed into a wellestablished treatment paradigm for solid cancers. As reflected by the increasing number of key publications in CVIR, several needle-guided thermal and non-thermal ablation techniques have evolved into reliable… read more here.
Keywords: ablation; insufficient rfa; tumour; ctla blockade ... See more keywords