A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14450
Abstract: Non-classical secretory vesicles, collectively referred to as extracellular vesicles (EVs), have been implicated in different aspects of cancer cell survival and metastasis. Here, we describe how a specific class of EVs, called microvesicles (MVs), activates… read more here.
Keywords: extracellular vesicles; vegf receptors; receptors tumour; activates vegf ... See more keywords
Tumour angiogenesis: Controlling nerves
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cancer"
DOI: 10.1038/nrc.2017.107
Abstract: Sympathetic nerves associate with tumours and regulate the tumour microenvironment. How this innervation promotes tumorigenesis is unclear. A new study in Scienceshows that β-adrenergic signalling controls tumour growth by promoting tumour angiogenesis, through the regulation… read more here.
Keywords: angiogenesis controlling; tumour angiogenesis; angiogenesis; controlling nerves ... See more keywords
The miR-200-Quaking axis functions in tumour angiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-0916-1
Abstract: The progression of solid cancers towards a metastatic state is facilitated by tumor angiogenesis. While targeting of angiogenesis is an important therapeutic strategy, its success has been limited by an incomplete understanding of tumor endothelial… read more here.
Keywords: angiogenesis; tumour angiogenesis; mir 200; cancer ... See more keywords
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17257
Abstract: Bladder cancer (BLCA) is a common genitourinary cancer in patients, and tumour angiogenesis is indispensable for its occurrence and development. However, the indepth mechanism of tumour angiogenesis in BLCA remains elusive. According to recent studies,… read more here.
Keywords: il8 stat3; angiogenesis; bladder cancer; tumour angiogenesis ... See more keywords
Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16969
Abstract: Delta-like 4 (DLL4) and Jagged1 (JAG1) are two key Notch ligands implicated in tumour angiogenesis. They were shown to have opposite effects on mouse retinal and adult regenerative angiogenesis. In tumours, both ligands are upregulated… read more here.
Keywords: angiogenesis; jag1; tumour growth; tumour angiogenesis ... See more keywords
The ALK1-Smad1/5-ID1 pathway participates in tumour angiogenesis induced by low-dose photodynamic therapy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Oncology"
DOI: 10.3892/ijo.2023.5503
Abstract: Photodynamic therapy (PDT) is an effective and low-invasive tumour therapy. However, it can induce tumour angiogenesis, which is a main factor leading to tumour recurrence and metastasis. Activin receptor-like kinase-1 (ALK1) is a key factor… read more here.
Keywords: tumour angiogenesis; dose pdt; alk1; angiogenesis ... See more keywords