Articles with "tumour burden" as a keyword



A logistic regression model predicting high axillary tumour burden in early breast cancer patients

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Published in 2017 at "Clinical and Translational Oncology"

DOI: 10.1007/s12094-017-1737-8

Abstract: PurposeAs elective axillary dissection is loosing ground for early breast cancer (BC) patients both in terms of prognostic and therapeutic power, there is a growing interest in predicting patients with (nodal) high tumour burden (HTB),… read more here.

Keywords: tumour burden; logistic regression; early breast; breast cancer ... See more keywords

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

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Published in 2017 at "Nature"

DOI: 10.1038/nature22079

Abstract: Despite the success of monotherapies based on blockade of programmed cell death 1 (PD-1) in human melanoma, most patients do not experience durable clinical benefit. Pre-existing T-cell infiltration and/or the presence of PD-L1 in tumours… read more here.

Keywords: tumour burden; cell; response; cell invigoration ... See more keywords

Enhancing the prognostic role of melanoma sentinel lymph nodes through microscopic tumour burden characterization: clinical usefulness in patients who do not undergo complete lymph node dissection

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Published in 2019 at "Melanoma Research"

DOI: 10.1097/cmr.0000000000000481

Abstract: This study aimed to investigate the sentinel lymph node (SLN) tumour burden to predict the non-SLN positivity rate and the survival of melanoma patients to evaluate whether SLN microstaging could predict the prognosis, similar to… read more here.

Keywords: lymph node; melanoma; non sln; tumour burden ... See more keywords

Assessment of skeletal tumour burden on 18F-NaF PET/CT using a new quantitative method

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Published in 2017 at "Nuclear Medicine Communications"

DOI: 10.1097/mnm.0000000000000654

Abstract: Purpose The purpose of this study was to test a method of quantifying skeletal tumour burden with 18F-NaF PET/CT. Patients and methods We retrospectively reviewed the charts of 117 patients who underwent 18F-NaF PET/CT for… read more here.

Keywords: tumour burden; 18f naf; naf pet; skeletal tumour ... See more keywords

Bendamustine and rituximab in elderly patients with low‐tumour burden follicular lymphoma. Results of the LYSA phase II BRIEF study

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Published in 2018 at "British Journal of Haematology"

DOI: 10.1111/bjh.15513

Abstract: The treatment of low‐tumour burden follicular lymphoma (LTBFL) remains a challenge. Rituximab‐based strategies may be improved by adding chemotherapy. This Lymphoma Study Association multicentre phase II study assessed rituximab and bendamustine in 63 patients with… read more here.

Keywords: tumour burden; lymphoma; low tumour; study ... See more keywords

Mutation profiling, tumour burden assessment, outcome prediction and disease monitoring by circulating tumour DNA in peripheral T-cell lymphoma.

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Published in 2023 at "British journal of haematology"

DOI: 10.1111/bjh.18824

Abstract: In this prospective study, we aimed to evaluate the utility of circulating tumour DNA (ctDNA) in peripheral T-cell lymphomas (PTCLs). Plasma cell-free DNA (cfDNA) was obtained, and the mutational profile was assessed in 47 patients… read more here.

Keywords: tumour burden; tumour dna; cell; circulating tumour ... See more keywords

Tumour Burden Reporting in Phase III Clinical Trials of Metastatic Lung, Breast, and Colorectal Cancers: A Systematic Review

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14133262

Abstract: Simple Summary The initial tumour burden is a strong and well-known prognostic factor in oncology. A systematic review was performed to examine if and how the initial tumour burden is reported in phase III clinical… read more here.

Keywords: clinical trials; disease; iii clinical; tumour burden ... See more keywords