Further insights into the role of tumour characteristics in survival of young women with epithelial ovarian cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.08.018
Abstract: OBJECTIVE Optimizing the counselling of women ≤40years with epithelial ovarian cancer (EOC) by investigating the role of young age and tumour characteristics on overall survival (OS). METHODS A retrospective population-based study was done using data… read more here.
Keywords: epithelial ovarian; survival young; tumour characteristics; ovarian cancer ... See more keywords
Tumour characteristics provide evidence for germline mismatch repair missense variant pathogenicity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2019-106096
Abstract: Background Pathogenic variants in mismatch repair (MMR) genes (MLH1, MSH2, MSH6 and PMS2) increase risk for Lynch syndrome and related cancers. We quantified tumour characteristics to assess variant pathogenicity for germline MMR genes. Methods Among… read more here.
Keywords: tumour characteristics; evidence; variant pathogenicity; missense ... See more keywords