Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-022-03179-4
Abstract: The importance of the tumour microbiome in different aspects of colorectal cancer (CRC) has been increasingly recognised, but many questions remain. The aim of this study was to explore the effect of specific CRC associated… read more here.
Keywords: cancer; parvimonas micra; tumour immune; immune profiles ... See more keywords
Investigating Macrophages Plasticity Following Tumour–Immune Interactions During Oncolytic Therapies
Sign Up to like & getrecommendations! Published in 2019 at "Acta Biotheoretica"
DOI: 10.1007/s10441-019-09357-9
Abstract: Over the last few years, oncolytic virus therapy has been recognised as a promising approach in cancer treatment, due to the potential of these viruses to induce systemic anti-tumour immunity and selectively killing tumour cells.… read more here.
Keywords: usepackage; immune responses; tumour immune; document ... See more keywords
Targeting the tumour immune microenvironment for cancer therapy in human gastrointestinal malignancies.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.05.017
Abstract: Gastrointestinal (GI) cancer is a malignancy of the GI tract and accessory digestive organs. GI cancer patients develop resistance to chemotherapy, targeted therapy drugs and immune therapies. Although immune checkpoint inhibitors have shown promising clinical… read more here.
Keywords: therapy; time; tumour immune; immune microenvironment ... See more keywords
Dynamic aspects of tumour–immune system interaction under a periodic immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Applied Mathematics"
DOI: 10.1017/s0956792521000152
Abstract: We study a mathematical model proposed in the literature with the aim of describing the interactions between tumor cells and the immune system, when a periodic treatment of immunotherapy is applied. Combining some techniques from… read more here.
Keywords: system; immune system; immunotherapy; dynamic aspects ... See more keywords
Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27936-8
Abstract: Therapeutic blockade of the immune checkpoint proteins programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA4) has transformed cancer treatment. However, the overall response rate to these treatments is low, suggesting… read more here.
Keywords: cancer; btnl2; tumour; producing cells ... See more keywords
Analysis of tumour-immune evasion with chemo-immuno therapeutic treatment with quadratic optimal control
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biological Dynamics"
DOI: 10.1080/17513758.2017.1381280
Abstract: ABSTRACT A simple mathematical model for the growth of tumour with discrete time delay in the immune system is considered. The dynamical behaviour of our system by analysing the existence and stability of our system… read more here.
Keywords: control; tumour immune; model; analysis tumour ... See more keywords
The functions of autophagy at the tumour‐immune interface
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DOI: 10.1111/jcmm.16331
Abstract: Autophagy is frequently induced in the hypoxic tumour microenvironment. Accumulating evidence reveals important functions of autophagy at the tumour‐immune interface. Herein, we propose an update on the roles of autophagy in modulating tumour immunity. Autophagy… read more here.
Keywords: immune interface; functions autophagy; autophagy tumour; tumour immune ... See more keywords
Annexin‐1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin‐8
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17458
Abstract: Annexin‐1 (ANXA1) is widely reported to be deregulated in various cancers and is involved in tumorigenesis. However, its effects on glioblastoma (GBM) remain unclear. Using immunohistochemistry with tissue microarrays, we showed that ANXA1 was overexpressed… read more here.
Keywords: upregulation; annexin; tumour immune; immune escape ... See more keywords
PO-392 Galectin-9 is required for dendritic cell function and directly contributes to DC-mediated anti-tumour immunity
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.904
Abstract: Introduction Dendritic cells (DCs) express a variety of cell surface receptors aimed at facilitating recognition, uptake and presentation of tumour antigens, which allows for the initiation of a potent anti-tumour immune response. Galectin-mediated interactions on… read more here.
Keywords: galectin; plasma membrane; tumour immune; anti tumour ... See more keywords
Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/2021613
Abstract: Background Hepatocellular carcinoma (HCC) is predominant among all types of primary liver cancers characterised by high morbidity and mortality. Genes in the mediator complex (MED) family are engaged in the tumour-immune microenvironment and function as… read more here.
Keywords: hepatocellular carcinoma; family; mediator complex; tumour immune ... See more keywords
Immune-related gene signature associates with immune landscape and predicts prognosis accurately in patients with Wilms tumour
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.920666
Abstract: Wilms tumour (WT) is the most common kidney malignancy in children. Chemoresistance is the leading cause of tumour recurrence and poses a substantial therapeutic challenge. Increasing evidence has underscored the role of the tumour immune… read more here.
Keywords: wilms tumour; signature; tumour immune; immune landscape ... See more keywords