Articles with "tumour mutation" as a keyword



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Clinical significance of tumour mutation burden in immunotherapy across multiple cancer types: an individual meta-analysis.

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Published in 2020 at "Japanese journal of clinical oncology"

DOI: 10.1093/jjco/hyaa076

Abstract: BACKGROUND Biomarkers for stratifying patients that could benefit from immune checkpoint inhibitors are necessary. Tumour mutation burden has recently become a promising biomarker in cancer, but the associations between tumour mutation burden and outcomes of… read more here.

Keywords: cancer; tumour mutation; mutation burden; meta analysis ... See more keywords
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A lncRNA prognostic signature associated with immune infiltration and tumour mutation burden in breast cancer

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Published in 2020 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.15762

Abstract: Current studies have shown that long nonā€coding RNAs (lncRNAs) may serve as prognostic biomarkers in multiple cancers. Therefore, we postulated that expression patterns of multiple lncRNAs combined into a single signature could improve clinicopathological risk… read more here.

Keywords: tumour mutation; breast cancer; mutation burden; signature ... See more keywords