Articles with "tumour organoid" as a keyword



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Generation and initial characterization of novel tumour organoid models to study human pancreatic cancer‐induced cachexia

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Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.12627

Abstract: The majority of patients with pancreatic cancer develops cachexia. The mechanisms underlying cancer cachexia development and progression remain elusive, although tumour‐derived factors are considered to play a major role. Pancreatic tumour organoids are in vitro… read more here.

Keywords: characterization novel; generation initial; pancreatic cancer; initial characterization ... See more keywords
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Human pancreatic tumour organoid‐derived factors enhance myogenic differentiation

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Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.12917

Abstract: Most patients with pancreatic cancer develop cachexia, which is characterized by progressive muscle loss. The mechanisms underlying muscle loss in cancer cachexia remain elusive. Pancreatic tumour organoids are 3D cell culture models that retain key… read more here.

Keywords: tumour organoid; pancreatic tumour; muscle; tumour ... See more keywords