A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images
Sign Up to like & getrecommendations! Published in 2017 at "European Radiology"
DOI: 10.1007/s00330-017-5154-8
Abstract: ObjectivesTo develop a model using radiomic features extracted from MR images to distinguish radiation necrosis from tumour progression in brain metastases after Gamma Knife radiosurgery.MethodsWe retrospectively identified 87 patients with pathologically confirmed necrosis (24 lesions)… read more here.
Keywords: radiomic features; tumour progression; radiation necrosis; necrosis tumour ... See more keywords
Anaesthesia as an influence in tumour progression
Sign Up to like & getrecommendations! Published in 2021 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-021-02078-z
Abstract: Tumour growth and the formation of metastases are essential elements in the progression of cancer. The centre of treatment is the surgical resection of primary solid tumours. But even if the tumour can be removed… read more here.
Keywords: tumour cells; anaesthesia influence; tumour progression; progression ... See more keywords
The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
Sign Up to like & getrecommendations! Published in 2017 at "Purinergic Signalling"
DOI: 10.1007/s11302-017-9593-0
Abstract: Seven P2X ion channel nucleotide receptor subtypes have been cloned and characterised. P2X7 receptors (P2X7R) are unusual in that there are extra amino acids in the intracellular C terminus. Low concentrations of ATP open cation… read more here.
Keywords: p2x7 receptors; tumour progression; potential p2x7; inflammation ... See more keywords
Suppression of angiogenesis and tumour progression by combretastatin and derivatives.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.06.032
Abstract: The search for small molecule inhibitors has gained prominence with the recognition of their inherent advantage for cancer therapy. Combretastatin is a naturally occurring small stilbenoid. By virtue of the ability to bind to tubulin… read more here.
Keywords: angiogenesis tumour; suppression angiogenesis; combretastatin derivatives; tumour progression ... See more keywords
ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-021-02017-8
Abstract: ISG15 is an ubiquitin-like modifier that is associated with reduced survival rates in breast cancer patients. The mechanism by which ISG15 achieves this however remains elusive. We demonstrate that modification of Rab GDP-Dissociation Inhibitor Beta… read more here.
Keywords: basal breast; isgylation; egfr recycling; tumour progression ... See more keywords
Age-induced accumulation of methylmalonic acid promotes tumour progression
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2630-0
Abstract: The risk of cancer and associated mortality increases substantially in humans from the age of 65 years onwards 1 – 6 . Nonetheless, our understanding of the complex relationship between age and cancer is still in… read more here.
Keywords: age; methylmalonic acid; promotes tumour; tumour progression ... See more keywords
Machine learning imaging applications in the differentiation of true tumour progression from treatment‐related effects in brain tumours: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Imaging and Radiation Oncology"
DOI: 10.1111/1754-9485.13436
Abstract: Chemotherapy and radiotherapy can produce treatment‐related effects, which may mimic tumour progression. Advances in Artificial Intelligence (AI) offer the potential to provide a more consistent approach of diagnosis with improved accuracy. The aim of this… read more here.
Keywords: related effects; treatment related; tumour progression; machine learning ... See more keywords
Newly discovered mechanisms that mediate tumorigenesis and tumour progression: circRNA-encoded proteins.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17751
Abstract: Proteins produced by cap-independent translation mediated by an internal ribosome entry site (IRES) in circular RNAs (circRNAs) play important roles in tumour progression. To date, numerous studies have been performed on circRNAs and the proteins… read more here.
Keywords: circrna encoded; tumour progression; newly discovered; encoded proteins ... See more keywords
TRIM27‐USP7 complex promotes tumour progression via STAT3 activation in human hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Liver International"
DOI: 10.1111/liv.15346
Abstract: TRIM27 is stabilized by binding to USP7 and mediates tumour progression in several cancers; however, the roles of TRIM27‐USP7 complex on STAT3 activation in HCC are unknown. read more here.
Keywords: usp7 complex; tumour progression; trim27 usp7; stat3 activation ... See more keywords
The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/6243819
Abstract: The function of natural killer (NK) cells, defending against virus infection and tumour progression, is regulated by multiple activating and inhibiting receptors expressed on NK cells, among which sialic acid-bind immunoglobulin-like lectins (Siglecs) act as… read more here.
Keywords: infection tumour; tumour progression; virus infection; siglec7 siglec9 ... See more keywords
MCM7 as a marker of postsurgical progression in non-functioning pituitary adenomas.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-20-1086
Abstract: OBJECTIVE Current markers predicting tumour progression of pituitary adenomas after surgery are insufficient. Our objective was to investigate if minichromosome maintenance protein 7 (MCM7) expression predicts tumour progression in non-functioning pituitary adenomas (NFPAs). METHODS In… read more here.
Keywords: expression; pituitary adenomas; mcm7; progression ... See more keywords