STAT3 signaling mediates tumour resistance to EGFR targeted therapeutics
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.01.010
Abstract: Several EGFR inhibitors are currently undergoing clinical assessment or are approved for the clinical management of patients with varying tumour types. However, treatment often results in a lack of response in many patients. The majority… read more here.
Keywords: egfr targeted; tumour resistance; signaling mediates; resistance ... See more keywords
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra07760j
Abstract: A new family of anticancer compounds has been derived from oxaliplatin by inserting a double-bond between carbons 4 and 5 of the 1,2-diaminocyclohexane ring. read more here.
Keywords: minimal structural; tumour resistance; overcome tumour; variation overcome ... See more keywords