Transport of drugs from blood vessels to tumour tissue
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cancer"
DOI: 10.1038/nrc.2017.93
Abstract: The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue depends on the… read more here.
Keywords: tumour tissue; transport; tissue; drug ... See more keywords
Resolution of paraneoplastic PM/Scl-positive systemic sclerosis after curative resection of a pancreatic tumour.
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kew382
Abstract: SIR, Compelling evidence has recently been presented that SSc may occur as a paraneoplastic disease, especially for cases expressing hallmark anti-RNA polymerase III autoantibodies [1]. Elegant studies have confirmed expression of variant protein by tumours… read more here.
Keywords: scl; resolution; tumour tissue; disease ... See more keywords
P173 Plasma and tumour tissue TP53-gene expression in patients with high grade serous advanced ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.233
Abstract: Introduction/Background TP53 is a tumour suppressor gene frequently mutated in high grade serous ovarian cancer(HGSOC).The aim of this study is to investigate the expression of TP5-gene in cell-free DNA(cfDNA) in plasma and tumour paraffin-embedded tissue… read more here.
Keywords: tumour tissue; expression; tissue; tp53 gene ... See more keywords
DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3206-8
Abstract: BackgroundTumour stem cells are considered important to promote disease progression, recurrence and treatment resistance following chemotherapy in colon cancer. However, genomic analyses of colorectal cancer have mainly been performed on integrated tumour tissue consisting of… read more here.
Keywords: tumour tissue; cd133 cd133; dna alterations; cell ... See more keywords
Assessing the Concordance of Genomic Alterations between Circulating-Free DNA and Tumour Tissue in Cancer Patients
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11121938
Abstract: Somatic alterations to the genomes of solid tumours, which in some cases represent actionable drivers, provide diagnostic and prognostic insight into these complex diseases. Spatial and longitudinal tracking of somatic genomic alterations (SGAs) in patient… read more here.
Keywords: tumour tissue; circulating free; cfdna; genomic alterations ... See more keywords