Total synthesis of interleukin-2 via a tunable backbone modification strategy
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DOI: 10.1039/d2sc05660g
Abstract: Chemical synthesis of hydrophobic proteins presents a formidable task as they are often difficultly achieved via peptide synthesis, purification, and peptide ligation. Thus, peptide solubilizing strategies are needed to integrate with peptide ligation to achieve… read more here.
Keywords: tunable backbone; modification strategy; synthesis; strategy ... See more keywords