Articles with "tunable brake" as a keyword



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A Tunable Brake for HECT Ubiquitin Ligases.

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Published in 2017 at "Molecular cell"

DOI: 10.1016/j.molcel.2017.03.020

Abstract: The HECT E3 ligases ubiquitinate numerous transcription factors and signaling molecules, and their activity must be tightly controlled to prevent cancer, immune disorders, and other diseases. In this study, we have found unexpectedly that peptide… read more here.

Keywords: hect ubiquitin; tunable brake; ubiquitin ligases; hect ... See more keywords