Antimicrobial tunicamycin derivatives from the deep sea-derived Streptomyces xinghaiensis SCSIO S15077
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DOI: 10.1080/14786419.2018.1493736
Abstract: Abstract Tunicamycin E (1), featuring a methyl substitution at C-10′, was isolated from marine-derived Streptomyces xinghaiensis SCSIO S15077 originated from the South China Sea sediment together with six known compounds, tunicamycin B (2), tunicamycin X… read more here.
Keywords: xinghaiensis scsio; scsio s15077; sea; derived streptomyces ... See more keywords
Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway
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DOI: 10.1097/cad.0000000000000431
Abstract: Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) is a cytokine that selectively induces apoptosis in many tumor cells while leaving normal cells intact and is thus an attractive candidate for antitumor therapies. This paper reports… read more here.
Keywords: trail; induced apoptosis; jnk chop; trail induced ... See more keywords
Structure-Based Insight on the Mechanism of N-Glycosylation Inhibition by Tunicamycin.
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DOI: 10.14348/molcells.2023.0001
Abstract: N-glycosylation, a common post-translational modification, is widely acknowledged to have a significant effect on protein stability and folding. N-glycosylation is a complex process that occurs in the endoplasmic reticulum (ER) and requires the participation of… read more here.
Keywords: mechanism; glycosylation; tunicamycin; gpt ... See more keywords
Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats
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DOI: 10.22038/ijbms.2022.58719.13043
Abstract: Objective(s): This study aimed to investigate the possible consequences of administering exogenous melatonin as prevention or treatment against tunicamycin-induced endoplasmic reticulum (ER) stress in the testicular tissue of rats. Materials and Methods: In this study,… read more here.
Keywords: stress testicular; tunicamycin induced; tunicamycin; testicular tissue ... See more keywords
Protective Effect of Zeaxanthin against Tunicamycin-induced Cell Damage in SH-SY5Y Cell
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DOI: 10.3136/fstr.24.1101
Abstract: Endoplasmic reticulum (ER) stress and the resulting neuronal cell damage have been implicated in the development and progression of Alzheimer’s disease. Tunicamycin (TM) induces ER stress in vitro, and the protective effects of the carotenoid… read more here.
Keywords: tunicamycin; cell damage; cell; zeaxanthin ... See more keywords
Tunicamycin Mediated Inhibition of Wall Teichoic Acid Affects Staphylococcus aureus and Listeria monocytogenes Cell Morphology, Biofilm Formation and Virulence
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DOI: 10.3389/fmicb.2018.01352
Abstract: The emergence of bacterial resistance to therapeutic antibiotics limits options for treatment of common microbial diseases. Subinhibitory antibiotics dosing, often aid in the emergence of resistance, but its impact on pathogen’s physiology and pathogenesis is… read more here.
Keywords: virulence; physiology; wall; resistance ... See more keywords