Tuning Cell-Free Composition Controls the Time Delay, Dynamics, and Productivity of TX-TL Expression.
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DOI: 10.1021/acssynbio.1c00136
Abstract: The composition of cell-free expression systems (TX-TL) is adjusted by adding macromolecular crowding agents and salts. However, the effects of these cosolutes on the dynamics of individual gene expression processes have not been quantified. Here,… read more here.
Keywords: tuning cell; time; cell free; expression ... See more keywords
Tuning up T-cell receptors
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DOI: 10.1038/nbt.4009
Abstract: T-cell receptors with higher affinity for tumor antigens are discovered by harnessing T-cell development. read more here.
Keywords: cell; tuning cell; cell receptors;
TCR tuning of T cell subsets
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DOI: 10.1111/imr.12646
Abstract: After selection in the thymus, the post‐thymic T cell compartments comprise heterogenous subsets of naive and memory T cells that make continuous T cell receptor (TCR) contact with self‐ligands bound to major histocompatibility complex (MHC)… read more here.
Keywords: cell; tcr tuning; tuning cell; cell subsets ... See more keywords