Regiodivergent Remote C-H Functionalization by Tuning Template Geometry.
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DOI: 10.1021/acs.orglett.4c01460
Abstract: For transition-metal-catalyzed C-H functionalization, precise differentiation between remote adjacent C(sp2)-H bonds remains a long-standing challenge. Here, the template structure-directivity relationship on remote C-H functionalization of arenes was experimentally and computationally studied. By using geometry-tunable templates,… read more here.
Keywords: regiodivergent remote; remote functionalization; tuning template; functionalization ... See more keywords