Super-resolution imaging of the dynamic cleavage of intercellular tunneling nanotubes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers of Optoelectronics"
DOI: 10.1007/s12200-020-1068-1
Abstract: As a new method of cell-cell communication, tunneling nanotubes (TNTs) play important roles in cell-cell signaling and mass exchanges. However, a lack of powerful tools to visualize dynamic TNTs with high temporal/spatial resolution restricts the… read more here.
Keywords: resolution; tunneling nanotubes; resolution imaging; microscopy ... See more keywords
Tunneling nanotubes: Reshaping connectivity.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2021.03.003
Abstract: Tunneling nanotubes (TNTs), open membranous channels between connected cells, represent a novel direct way of communication between distant cells for the diffusion of various cellular material, including survival or death signals, genetic material, organelles, and… read more here.
Keywords: tunneling nanotubes; communication; biology; nanotubes reshaping ... See more keywords
Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2110329119
Abstract: Significance The current lack of understanding of the mechanisms leading to neurovascular deficits in glaucoma is a major knowledge gap in the field. Retinal pericytes regulate microcirculatory blood flow and coordinate neurovascular coupling through interpericyte… read more here.
Keywords: neurovascular coupling; tunneling nanotubes; interpericyte tunneling; blood ... See more keywords
Tunneling nanotubes and mesenchymal stem cells: New insights into the role of melatonin in neuronal recovery
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12800
Abstract: Efficient cell‐to‐cell communication is essential for tissue development, homeostasis, and the maintenance of cellular functions after injury. Tunneling nanotubes (TNTs) have emerged as a new important method of cell‐to‐cell communication. TNTs are primarily established between… read more here.
Keywords: tunneling nanotubes; cell; nanotubes mesenchymal; role ... See more keywords
Formation of cellular close-ended tunneling nanotubes through mechanical deformation
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abj3995
Abstract: Membrane nanotubes or tunneling nanotubes (TNTs) that connect cells have been recognized as a previously unidentified pathway for intercellular transport between distant cells. However, it is unknown how this delicate structure, which extends over tens… read more here.
Keywords: tunneling nanotubes; close ended; formation cellular; dfb ... See more keywords
Tunneling nanotubes provide a route for SARS-CoV-2 spreading
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo0171
Abstract: Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection represent a major issue in long coronavirus disease. How SARS-CoV-2 gains access to the brain and how infection leads to neurological symptoms are not… read more here.
Keywords: tunneling nanotubes; infection; route; cov spreading ... See more keywords
Rab11a–Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.215889
Abstract: ABSTRACT Tunneling nanotubes (TNTs) are actin-enriched membranous channels enabling cells to communicate over long distances. TNT-like structures form between various cell types and mediate the exchange of different cargos, such as ions, vesicles, organelles and… read more here.
Keywords: tunneling nanotubes; rab11a rab8a; number tnt; formation ... See more keywords
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Reports"
DOI: 10.15252/embr.202052006
Abstract: Abstract Tunneling nanotubes (TNTs) are actin‐rich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs transport signaling molecules, vesicles, organelles, and even pathogens. However, the molecular mechanisms regulating… read more here.
Keywords: tunneling nanotubes; mitochondrial trafficking; modulates mitochondrial; mical2pv ... See more keywords
Influence of α-Particle Radiation on Intercellular Communication Networks of Tunneling Nanotubes in U87 Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.01691
Abstract: Cellular communication plays a crucial role in the coordination and organization of cancer cells. Especially processes such as uncontrolled cell growth, invasion, and therapy resistance (development), which are features of very malignant tumors like glioblastomas,… read more here.
Keywords: tunneling nanotubes; communication; u87 glioblastoma; glioblastoma cells ... See more keywords
Intercellular Communication in the Brain through Tunneling Nanotubes
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14051207
Abstract: Simple Summary Tunneling nanotubes (TNTs) are a means of cell communication which have been recently discovered. They allow the intercellular trafficking of many types of cellular compounds ranging from ions, such as Ca2+, to whole… read more here.
Keywords: tunneling nanotubes; function; intercellular communication; communication ... See more keywords
TNTdetect.AI: A Deep Learning Model for Automated Detection and Counting of Tunneling Nanotubes in Microscopy Images
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14194958
Abstract: Simple Summary Microscopy is central to many areas of biomedical science research, including cancer research, and is critical for understanding basic pathophysiology, mechanisms of action, and treatment response. However, analysis of the numerous images generated… read more here.
Keywords: tunneling nanotubes; microscopy; microscopy images; model ... See more keywords