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   Articles with "tusc3" as a keyword



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TUSC3: a novel tumour suppressor gene and its functional implications

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recommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.13128

Abstract: The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N‐glycosylation of nascent proteins.… read more here.

Keywords: suppressor gene; tusc3; tumour suppressor; tumour ... See more keywords
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TUSC3 inhibits cell proliferation and invasion in cervical squamous cell carcinoma via suppression of the AKT signalling pathway

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recommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17204

Abstract: The decreased expression of tumour suppressor candidate 3 (TUSC3) is associated with proliferation in several types of cancer, leading to an unfavourable prognosis. The present study aimed to assess the cellular and molecular function of… read more here.

Keywords: akt signalling; cell; tusc3; proliferation ... See more keywords
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Biological role of TUSC3 in non-small-cell lung cancer.

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recommendations! Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.e24213

Abstract: e24213Background: The tumor suppressor candidate 3 (TUSC3) gene is located on chromosome 8p22 and is universally acknowledged as a cancer suppressor. But our previous research has demonstrated that... read more here.

Keywords: tusc3 non; tusc3; non small; cancer ... See more keywords
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Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.20950

Abstract: Colorectal cancer (CRC) is a biologically and clinically heterogeneous disease. Even though many recurrent genomic alterations have been identified that may characterize distinct subgroups, their biological impact and clinical significance as prognostic indicators remain to… read more here.

Keywords: epigenetic silencing; tumor suppressor; colorectal cancer; crc ... See more keywords
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The LncRNA MIR503HG/miR-224-5p/TUSC3 Signaling Cascade Suppresses Gastric Cancer Development via Modulating ATF6 Branch of Unfolded Protein Response

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recommendations! Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.708501

Abstract: Background Unfolded protein response (UPR)-mediated tumor-promoting functions have been identified in multiple cancers, and this study focused on investigating the role and molecular mechanisms of UPR in modulating gastric cancer (GC) pathogenesis. Methods The bioinformatics… read more here.

Keywords: lncrna mir503hg; unfolded protein; mir 224; cancer ... See more keywords