The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome‐Induced Inflammation
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DOI: 10.1016/j.immuni.2018.04.032
Abstract: Summary Potassium (K+) efflux across the plasma membrane is thought to be an essential mechanism for ATP‐induced NLRP3 inflammasome activation, yet the identity of the efflux channel has remained elusive. Here we identified the two‐pore… read more here.
Keywords: nlrp3 inflammasome; channel; twik2; potassium efflux ... See more keywords