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Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14010184

Abstract: The performance of solid oral dosage forms targeting the colon is typically evaluated using standardised pharmacopeial dissolution apparatuses. However, these fail to replicate colonic hydrodynamics. This study develops a digital twin of the Dynamic Colon… read more here.

Keywords: digital twin; dynamic colon; model; colon model ... See more keywords