Estimating Heritability from Twin Studies.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7274-6_9
Abstract: This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions, and some possible… read more here.
Keywords: heritability twin; chapter; heritability; twin studies ... See more keywords
Comment on “Epigenetics in the pathogenesis of RA”
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-017-0638-9
Abstract: Dear Editors, Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects between 0.5 and 1% of individuals in the more economically developed countries [1]. The cause of the disease is yet to be determined,… read more here.
Keywords: dmrs; immunopathology; study; twin pairs ... See more keywords
Genetic and environmental factors of schizophrenia and autism spectrum disorder: insights from twin studies
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DOI: 10.1007/s00702-020-02188-w
Abstract: Twin studies of psychiatric disorders such as schizophrenia and autism spectrum disorder have employed epidemiological approaches that determine heritability by comparing the concordance rate between monozygotic twins (MZs) and dizygotic twins. The basis for these… read more here.
Keywords: schizophrenia autism; environmental factors; psychiatric disorders; spectrum disorder ... See more keywords
What Twin Studies Tell Us About Brain Responses to Food Cues
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DOI: 10.1007/s13679-017-0282-7
Abstract: Purpose of ReviewFunctional magnetic resonance imaging (fMRI) using visual food cues provides insight into brain regulation of appetite in humans. This review sought evidence for genetic determinants of these responses.Recent FindingsEchoing behavioral studies of food… read more here.
Keywords: food cues; twin studies; studies tell; obesity ... See more keywords
Executive Functions and Impulsivity Are Genetically Distinct and Independently Predict Psychopathology: Results From Two Adult Twin Studies
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DOI: 10.1177/2167702619898814
Abstract: Laboratory executive function (EF) constructs, such as response inhibition, are often conceptually linked with self-report measures of impulsivity, yet their empirical correlations are low. We examined, in two twin studies (ns = 749 and 761… read more here.
Keywords: impulsivity dimensions; executive functions; psychopathology results; twin studies ... See more keywords
Idiopathic scoliosis: a systematic review and meta-analysis of heritability
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DOI: 10.1530/eor-22-0026
Abstract: Purpose Idiopathic scoliosis is the most common spinal deformity and affects 1–3% of children and adolescents. Idiopathic scoliosis may run in families and the purpose of this systematic review was to describe the degree of… read more here.
Keywords: scoliosis; heritability; twin studies; heritability estimates ... See more keywords
Can We Validate the Results of Twin Studies? A Census-Based Study on the Heritability of Educational Achievement
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2017.00160
Abstract: As for most phenotypes, the amount of variance in educational achievement explained by SNPs is lower than the amount of additive genetic variance estimated in twin studies. Twin-based estimates may however be biased because of… read more here.
Keywords: validate results; census based; heritability; educational achievement ... See more keywords