Duplex Sequencing Accurately Detects Variants below 1/100,000 in Genes Recurrently Mutated in Acute Myeloid Leukemia
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DOI: 10.1182/blood-2018-99-115071
Abstract: Acute myeloid leukemia (AML) is a challenging disease to treat: most patients achieve remission after induction chemotherapy, but the majority eventually relapse. Minimal residual disease (MRD) after initial treatment is the best predictor of relapse… read more here.
Keywords: dna; 100 000; duplex; duplex sequencing ... See more keywords