TGFβ instructs mTORC2 to activate PKCβII for increased TWIST1 expression in proximal tubular epithelial cell injury
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DOI: 10.1002/1873-3468.14599
Abstract: The plasticity of proximal tubular epithelial cells in response to TGFβ contributes to the expression of TWIST1 to drive renal fibrosis. The mechanism of TWIST1 expression is not known. We show that both PI3 kinase… read more here.
Keywords: cell; proximal tubular; expression; twist1 expression ... See more keywords