Constitutive expression of spliced XBP1 causes perinatal lethality in mice
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DOI: 10.1002/dvg.23420
Abstract: Upon endoplasmic reticulum (ER) stress, inositol‐requiring enzyme 1 (IRE1) is activated and catalyzes nonconventional splicing of an unspliced X‐box binding protein 1 (XBP1U) mRNA to yield a spliced XBP1 (XBP1S) mRNA that encodes a potent… read more here.
Keywords: spliced xbp1; xbp1s; xbp1cs; twist2 cre ... See more keywords