Substrate Reduction Therapy for Krabbe Disease: Exploring the Repurposing of the Antibiotic D-Cycloserine
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DOI: 10.3389/fped.2021.807973
Abstract: Krabbe disease is a lysosomal storage disease that is caused by a deficiency in galactosylceramidase. Infantile onset disease is the most common presentation, which includes progressive neurological deterioration with corresponding demyelination, development of globoid cells,… read more here.
Keywords: therapy; cycloserine; twitcher mice; disease ... See more keywords