Two Catalytic Annulation Modes via Cu-Allenylidenes with Sulfur Ylides that Are Dominated by the Presence or Absence of Trifluoromethyl Substituents
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DOI: 10.1016/j.isci.2020.100994
Abstract: Summary We disclose the Cu-catalyzed enantioselective synthesis of 3-methyl-3-propargyl-indolines, which contain a quaternary stereogenic carbon center, via the decarboxylative [4 + 1] annulation of 4-methyl-4-propargyl-benzoxazinanones with variety of sulfur ylides. The reaction proceeds predominantly through… read more here.
Keywords: annulation; allenylidene intermediates; sulfur ylides; attack allenylidene ... See more keywords
A chitinase with two catalytic domains is required for organization of the cuticular extracellular matrix of a beetle
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DOI: 10.1371/journal.pgen.1007307
Abstract: Insect cuticle or exoskeleton is an extracellular matrix formed primarily from two different structural biopolymers, chitin and protein. During each molt cycle, a new cuticle is deposited simultaneously with degradation of the inner part of… read more here.
Keywords: extracellular matrix; matrix; catalytic domains; cuticle ... See more keywords
Organocatalysis and Beyond: Activating Reactions with Two Catalytic Species
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DOI: 10.3390/catal9110928
Abstract: Since the beginning of the millennium, organocatalysis has been gaining a predominant role in asymmetric synthesis and it is, nowadays, a foundation of catalysis. Synergistic catalysis, combining two or more different catalytic cycles acting in… read more here.
Keywords: activating reactions; reactions two; organocatalysis beyond; beyond activating ... See more keywords