Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX-2 inhibitory activity.
Sign Up to like & getrecommendations! Published in 2017 at "Chirality"
DOI: 10.1002/chir.22724
Abstract: The capacity of nonsteroidal antiinflammatory drugs (NSAIDs) to prevent prostanoids biosynthesis through the inhibition of COX-2 enzyme is related to their structural backbone, based on the fusion of a cis-stilbene unit with a variety of… read more here.
Keywords: chiral sulfoxides; two chiral; characterization two; enantioresolution stereochemical ... See more keywords
Two Chiral Metal Complex Templated Aluminoborates Constructed from Three Types of Oxoboron Clusters.
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DOI: 10.1021/acs.inorgchem.1c00384
Abstract: The two acentric aluminoborates (ABOs) [M(dap)3]2{Al[B5O7(OH)3][B5O8(OH)2][B6O9(OH)2]} (M and dap represent Co(1)/Ni(2) and 1,2-diaminopropane, respectively) templated by chiral metal complexes (CMCs) have been solvothermally synthesized. The isostructural 1 and 2 crystallize in the chiral space group… read more here.
Keywords: metal complex; wavelike layers; two chiral; chiral metal ... See more keywords
Coexistence of Two Chiral Helices Produces Kink Translation in Spiroplasma Swimming
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bacteriology"
DOI: 10.1128/jb.00735-19
Abstract: Many swimming bacteria generate a propulsion force by rotating helical filaments like a propeller. However, the nonflagellated bacteria Spiroplasma spp. swim without the use of the appendages. The tiny wall-less bacteria possess two chiral helices… read more here.
Keywords: coexistence; translation; body; cell ... See more keywords