Combination of IM-Based Approaches to Unravel the Coexistence of Two Conformers on a Therapeutic Multispecific mAb
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c00928
Abstract: Multispecific antibodies, which target multiple antigens at once, are emerging as promising therapeutic entities to offer more effective treatment than conventional monoclonal antibodies (mAbs). However, these highly complex mAb formats pose significant analytical challenges. We… read more here.
Keywords: mab; multispecific; coexistence two; two conformers ... See more keywords
Rotational spectroscopy of the two conformers of 3-methylbutyronitrile (C_4H_9CN) between 2 and 400 GHz
Sign Up to like & getrecommendations! Published in 2018 at "Astronomy and Astrophysics"
DOI: 10.1051/0004-6361/201832994
Abstract: We present high-resolution rotational spectroscopy of the two conformers of 3-methylbutyronitrile (C_4H_9CN). Spectra were taken between 2 and 24 GHz by means of Fourier transform microwave spectroscopy. Spectra between 36 and 403 GHz were recorded… read more here.
Keywords: methylbutyronitrile 9cn; rotational spectroscopy; conformers methylbutyronitrile; spectroscopy ... See more keywords
Hirshfeld Surfaces and Nonlinear Optics on Two Conformers of a Heterocyclic Chalcone
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Brazilian Chemical Society"
DOI: 10.21577/0103-5053.20170136
Abstract: Heterocyclic chalcones have been prominent in the scientific community due to various biological activities reported for these compounds. The structural knowledge of heterocyclic chalcones can help in the understanding of their mechanism of action. The… read more here.
Keywords: surfaces nonlinear; hirshfeld surfaces; heterocyclic chalcone; optics ... See more keywords