Articles with "two genotoxic" as a keyword



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Detection of Two Genotoxic Impurities in Drug Substance and Preparation of Imatinib Mesylate by LC–MS/MS

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Published in 2020 at "Chromatographia"

DOI: 10.1007/s10337-020-03903-1

Abstract: Abstract As a potential DNA damaging substance, genotoxic impurities have been concerned by regulatory authorities in various countries. Two genotoxic impurities were found in imatinib mesylate which was a classical small molecule inhibitor of tyrosine… read more here.

Keywords: two genotoxic; substance; drug; imatinib mesylate ... See more keywords