Generation of two isogenic knockout PKD2 iPS cell lines, IRFMNi003-A-1 and IRFMNi003-A-2, using CRISPR/Cas9 technology.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101667
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent inherited renal disease, characterized by multiple cysts that can lead to kidney failure resulting in end-stage renal disease. ADPKD is mainly caused by mutations in… read more here.
Keywords: two isogenic; crispr cas9; pkd2; cas9 technology ... See more keywords
Hepatic glucose metabolic responses to digestible dietary carbohydrates in two isogenic lines of rainbow trout
Sign Up to like & getrecommendations! Published in 2018 at "Biology Open"
DOI: 10.1242/bio.032896
Abstract: ABSTRACT Rainbow trout (Oncorhynchus mykiss) was recognized as a typical ‘glucose-intolerant’ fish and poor dietary carbohydrate user. Our first objective was to test the effect of dietary carbohydrates themselves (without modification of dietary protein intake)… read more here.
Keywords: two isogenic; dietary carbohydrates; isogenic lines; rainbow trout ... See more keywords