The α/β Hydrolase AzpM Catalyzes Dipeptide Synthesis in Alazopeptin Biosynthesis Using Two Molecules of Carrier Protein‐Tethered Amino Acid
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100700
Abstract: During the biosynthesis of alazopeptin, a tripeptide composed of two molecules of 6‐diazo‐5‐oxo‐L‐norleucine (DON) and one of alanine, the α/β hydrolase AzpM synthesizes the DON‐DON dipeptide using DON tethered to the carrier protein AzpF (DON‐AzpF).… read more here.
Keywords: azpf; two molecules; carrier protein; azpm ... See more keywords
AI-Driven prediction of binding trends of SARS-CoV-2 variants from atomistic simulations
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DOI: 10.1016/j.bpj.2021.11.1211
Abstract: Protein-protein interactions are fundamental for cellular processes underlying functions such as signal transduction, cell regulation, or immune response activation among others. However, in silico characterization at atomistic level of the binding process between two proteins… read more here.
Keywords: driven prediction; two molecules; prediction binding; prediction ... See more keywords
Hydroxyphenylamine phosphonate derivatives: Synthesis, X-ray crystallographic analysis, and evaluation of theirs anti-Alzheimer effects and antioxidant activities
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DOI: 10.1016/j.molstruc.2020.129121
Abstract: Abstract The present study deals with the synthesis and characterization by single-crystal X-ray analysis, UV-Vis and FT-IR spectroscopy of two new α-aminophosphonates molecules: ((2-Hydroxy-5-methyl-phenylamino)-phenyl-methyl)-phosphonic acid diethyl ester (MAPH) and ((2-Hydroxy-5-nitro-phenylamino)-phenyl-methyl)-phosphonic acid diethyl ester (NAPH), based… read more here.
Keywords: analysis; phosphonate derivatives; maph; two molecules ... See more keywords
Metal-free transfer hydrochlorination of internal C-C triple bonds with a bicyclo[3.1.0]hexane-based surrogate releasing two molecules of hydrogen chloride.
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DOI: 10.1039/d1cc06591b
Abstract: The development and application of a transfer hydrochlorination reagent based on a trichlorinated bicyclo[3.1.0]hexane core that transfers two molecules of HCl per molecule of surrogate to a π-basic substrate under B(C6F5)3 catalysis is reported. Lewis… read more here.
Keywords: bicyclo hexane; two molecules; transfer hydrochlorination;
Graphene catalyzes the reversible formation of a C–C bond between two molecules
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DOI: 10.1126/sciadv.aau9366
Abstract: Graphene grown on a transition metal surface catalyzes a reversible C–C bond–forming reaction between two molecules. Carbon deposits are well-known inhibitors of transition metal catalysts. In contrast to this undesirable behavior, here we show that… read more here.
Keywords: bond; catalyzes reversible; two molecules; formation bond ... See more keywords