Transcriptome analysis of two structurally related flavonoids; Apigenin and Chrysin revealed hypocholesterolemic and ketogenic effects in mouse embryonic fibroblasts.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173804
Abstract: There is no known single therapeutic drug for treating hypercholesterolemia that comes with negligible systemic side effects. In the current study, using next generation RNA sequencing approach in mouse embryonic fibroblasts we discovered that two… read more here.
Keywords: embryonic fibroblasts; two structurally; chrysin; apigenin chrysin ... See more keywords
A Comparative Study on the Performance of Inert and Functionalized Spheres Coated with Solid Dispersions Made of Two Structurally Related Antifungal Drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00482
Abstract: Fluid bed coating offers potential advantages as a formulation platform for amorphous solid dispersions (ASDs) of poorly soluble drugs, being a one-step manufacturing process which could reduce the risk of phase separation associated with multiple… read more here.
Keywords: two structurally; microscopy; pos; solid dispersions ... See more keywords
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00088
Abstract: The formation of misfolded protein oligomers during early stages of amyloid aggregation and the activation of the inflammatory response are two characteristic events associated with the onset and progression of a wide range of neurodegenerative… read more here.
Keywords: protein; response; two structurally; misfolded protein ... See more keywords
Ratiometric rapid distinction of two structurally similar fluoroquinolone antibiotics by a Tb/Eu hydrogel
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra03668a
Abstract: Norfloxacin and ofloxacin are two frequently prescribed second-generation fluoroquinolone antibiotics with an identical 4-quinolone chromophore and hence, are difficult to distinguish by conventional methods (UV or fluorescence). We have designed a Tb3+/Eu3+/cholate cocktail that enabled… read more here.
Keywords: two structurally; distinction two; fluoroquinolone; ratiometric rapid ... See more keywords