Association of Intravenous Tranexamic Acid With Thromboembolic Events and Mortality: A Systematic Review, Meta-analysis, and Meta-regression.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA surgery"
DOI: 10.1001/jamasurg.2021.0884
Abstract: Importance Tranexamic acid (TXA) is an efficient antifibrinolytic agent; however, concerns remain about the potential adverse effects, particularly vascular occlusive events, that may be associated with its use. Objective To examine the association between intravenous… read more here.
Keywords: risk; analysis; mortality; association ... See more keywords
Impact on blood loss and transfusion rates following administration of tranexamic acid in major oncological abdominal and pelvic surgery: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of surgical oncology"
DOI: 10.1002/jso.26900
Abstract: BACKGROUND AND OBJECTIVES Major bleeding and receiving blood products in cancer surgery are associated with increased postoperative complications and worse outcomes. Tranexamic acid (TXA) reduces blood loss and improves outcomes in various surgical specialities. We… read more here.
Keywords: blood; blood loss; abdominal pelvic; surgery ... See more keywords
Comment on the article “The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial”
Sign Up to like & getrecommendations! Published in 2020 at "International Orthopaedics"
DOI: 10.1007/s00264-020-04554-5
Abstract: To the Editor, I have read with great interest the article by Lei et al.—it has been an edifying experience to come across such a clinically relevant and important research where the authors have sought… read more here.
Keywords: initial dose; tranexamic acid; total knee; high initial ... See more keywords
Invited Commentary: A Decade Older Polytrauma Patients Do As Well Without As the Younger Ones with Tranexamic Acid
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Surgery"
DOI: 10.1007/s00268-021-06253-7
Abstract: CRASH-2, with over 20,000 subjects recruited in a trauma trial, found that the early administration of tranexamic acid (TXA) reduced all-cause mortality and the risk of death due to blood loss [1]. The uptake of… read more here.
Keywords: trial; tranexamic acid; trauma; older polytrauma ... See more keywords
Tranexamic acid usage in hip fracture surgery: a meta-analysis and meta-regression analysis of current practice
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-021-04231-1
Abstract: The use of tranexamic acid (TXA) in hip fracture surgery remains inconclusive. The aim of the present meta-analysis was to assess the role of TXA use in hip fracture surgery, and attempt to disclose possible… read more here.
Keywords: surgery; analysis; meta; hip fracture ... See more keywords
Are The Applications of Tranexamic Acid in Reverse Hybrid Total Knee Arthroplasty (TKA) The Same as Those in Fully Cemented TKA?: A Randomized Controlled Trial
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DOI: 10.1007/s12325-021-01719-5
Abstract: Traditional fully cemented prosthesis for total knee arthroplasty (TKA) has many disadvantages. Current studies have shown that the effects of mixed fixation TKA are the same as or even better than those of fully cemented… read more here.
Keywords: tka; cemented tka; fully cemented; txa ... See more keywords
Tranexamic acid in the treatment of post‐partum hemorrhage in the united states: a cost‐effectiveness analysis: 748
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DOI: 10.1016/j.ajog.2018.11.771
Abstract: 748 Tranexamic acid in the treatment of post-partum hemorrhage in the united states: a cost-effectiveness analysis Leanna S. Sudhof, Scott A. Shainker, Brett D. Einerson Beth Israel Deaconess Medical Center, Boston, MA, Harvard Medical School,… read more here.
Keywords: pph; analysis; treatment; hemorrhage ... See more keywords
Efficacy and Systemic Absorption of Peri-articular Versus Intra-articular Administration of Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial
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DOI: 10.1016/j.artd.2021.06.005
Abstract: Background Tranexamic acid (TXA) is widely accepted as an effective method for reducing blood loss after total knee arthroplasty (TKA). As different routes of local TXA administration have been proposed to minimize systemic complications, we… read more here.
Keywords: administration; tranexamic acid; blood loss; total knee ... See more keywords
Effect of Tranexamic Acid on Prevention of Hemorrhagic Mass Growth in Patients with Traumatic Brain Injury.
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DOI: 10.1016/j.wneu.2017.10.075
Abstract: BACKGROUND Intracranial hemorrhage is a common complication of traumatic brain injury (TBI). The purpose of this study is evaluation of the effect of tranexamic acid (TXA) on hemorrhagic mass growth in TBI patients. PATIENTS AND… read more here.
Keywords: mass; group; effect; brain ... See more keywords
Comparing &egr;‐Aminocaproic Acid and Tranexamic Acid in Reducing Postoperative Transfusions in Total Knee Arthroplasty
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DOI: 10.1055/s-0036-1593362
Abstract: Abstract Multiple studies have shown tranexamic acid (TXA) to reduce blood loss and transfusion rates in patients undergoing total knee arthroplasty (TKA). Accordingly, TXA has become a routine blood conservation agent for TKA. In contrast,… read more here.
Keywords: tranexamic acid; tka; total knee; acid ... See more keywords
Effect of Multiple Doses of Oral Tranexamic Acid on Haemostasis and Inflammatory Reaction in Total Hip Arthroplasty: A Randomized Controlled Trial.
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DOI: 10.1055/s-0038-1676625
Abstract: Tranexamic acid (TXA) reduces surgical blood loss and alleviates inflammatory response in total hip arthroplasty. However, studies have not identified an optimal regimen. The objective of this study was to identify the most effective regimen… read more here.
Keywords: oral txa; group; blood loss; txa ... See more keywords